
Cytherea has garnered much attention for her work in the adult film industry, winning the Best New Starlet Award from AVN in 2005. To date she has been featured in over 200 adult films, including the Squirtwoman trilogy (Cytherea Iz Squirtwoman, Squirtwoman 2 & 3). She has appeared on cable television shows, most notably the HBO/Cinemax series Sex Games: Vegas, Playboy TV's Night Calls and has been a three time guest of The Howard Stern Show (per her IMDb filmography).
Cytherea also hosted an industry talk and interview radio show with her husband Brian (also known as Plus One) on KSEX in Los Angeles, California called Goddess of Gush. According to her website, she lost her show in 2006. Together, Cytherea and her husband, have formed a production company called Club Cytherea Productions. Since its inception, 7 movies have been produced under the label, e.g. Female Ejaculation Nation, Meet The Fuckers and Star Whores.
After mentioning several times that she would not attempt an anal scene, Cytherea finally gave in to public pressure
and performed her first anal scene in the movie Anal Whores.